Name: Comforting Chicken and Stuffing Casserole for Busy Nights
Prep time: 15 min
Cook time: 45 min
Total time: 60 min
Ingredients: 2 lbs chicken tenderloins (can substitute with boneless, skinless chicken thighs or turkey); 0.5 tsp kosher salt; 0.5 tsp black pepper; 1 can cream of celery soup (or homemade white sauce for a lighter option); 1 can cream of chicken soup (can substitute based on dietary needs); 0.25 cup milk (adjust for creaminess preference); 1 box Stove Top chicken stuffing mix (or use homemade seasoned bread cubes); 1.5 cups chicken broth (low-sodium recommended)

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The other night, as I rummaged through my fridge, I stumbled upon two leftover rotisserie chicken breasts. That’s when inspiration struck; I was determined to transform them into something warm and comforting. Enter my Easy Chicken and Stuffing Casserole, the ultimate quick dinner that takes barely any time to whip up. This one-dish meal is perfect for busy evenings, delivering all the satisfying flavors of home-cooked comfort food without the fuss. The creamy sauce melds beautifully with tender chicken and a delightful crispy topping, which is always a hit around the dinner table. Whether you’re feeding a crowd or just a small family, this casserole will surely bring everyone back for seconds. Curious how this simple dish can become a weeknight favorite in your kitchen? Let’s dive in!

Why is This Casserole a Must-Try?

Simplicity at Its Best: No complicated steps here! This Easy Chicken and Stuffing Casserole can be on your table in no time, making it your go-to for hectic weeknights.

Deliciously Comforting: Each bite combines tender chicken with a rich sauce and a crispy stuffing topping, offering a hearty taste that warms the soul.

Great for Leftovers: Have leftover rotisserie chicken? This dish transforms it into something extraordinary, minimizing waste and maximizing flavor.

One-Dish Wonder: Cleanup is a breeze since everything cooks in one baking dish, leaving you more time to relax with loved ones.

Whether served alongside a fresh salad or paired with green beans, this casserole promises to become a staple in your home! If you’re looking for more simple dinner ideas, check out my recipes for Hot Honey Chicken and Cheesy Garlic Chicken.

Chicken and Stuffing Casserole Ingredients

For the Casserole
• Chicken Tenderloins – The star protein that keeps the dish tender; feel free to swap in boneless, skinless chicken thighs or even turkey for variety.
• Kosher Salt – Enhances all the flavors; ½ teaspoon is just the right amount.
• Black Pepper – Adds a subtle spice to elevate your casserole.
• Cream of Celery Soup – Creates a luscious base; replace with a homemade white sauce for a lighter twist if desired.
• Cream of Chicken Soup – Complements the flavors beautifully; can be swapped based on your dietary needs.
• Milk – Helps achieve a smooth consistency in the sauce; adjust to your taste for creaminess.
• Stove Top Chicken Stuffing Mix – Adds delightful texture and flavor; use homemade seasoned bread cubes for a personal touch.
• Chicken Broth – Moistens the stuffing for a perfect bake; low-sodium broth is a great option for reduced saltiness.

This Chicken and Stuffing Casserole is bound to become a weeknight hero, making mealtime feel cozy and indulgent with minimal effort.

Step‑by‑Step Instructions for Chicken and Stuffing Casserole

Step 1: Preheat the Oven
Begin by preheating your oven to 375°F (190°C). This ensures your Chicken and Stuffing Casserole bakes evenly and thoroughly. While the oven heats up, gather your ingredients and prep your baking dish for a smooth cooking experience.

Step 2: Prepare the Baking Dish
Spray an 11×7-inch baking dish with cooking spray to prevent sticking. This handy step will help in keeping your Chicken and Stuffing Casserole intact when serving. Set the dish aside, ready to receive the delicious layers of flavor to come.

Step 3: Cut the Chicken
Take 2 lbs of chicken tenderloins and cut them into bite-sized pieces, which will cook evenly throughout the dish. Spread the chicken pieces evenly across the prepared baking dish for a uniform base. This way, each bite of your casserole is packed with tender chicken goodness.

Step 4: Season the Chicken
Sprinkle ½ teaspoon of kosher salt and ½ teaspoon of black pepper over the chicken pieces. Use your hands or a spoon to toss gently, ensuring that the seasoning envelops each piece. This simple seasoning will enhance the overall flavor of your Chicken and Stuffing Casserole.

Step 5: Whisk the Sauces
In a small bowl, whisk together one can each of cream of celery soup and cream of chicken soup with ¼ cup of milk until the mixture is smooth and creamy. This delicious sauce will provide richness to the casserole, so make sure there are no lumps before pouring over the chicken.

Step 6: Combine Chicken and Sauce
Pour the creamy sauce evenly over the seasoned chicken, making sure every bit of chicken is well-coated. The sauce acts as a delightful binder, ensuring that your Chicken and Stuffing Casserole is both moist and flavorful as it bakes.

Step 7: Add the Stuffing
Sprinkle a box of Stove Top chicken stuffing mix generously over the top of the sauce-covered chicken. This layer adds texture and that signature comforting taste that pairs perfectly with the creamy filling. Make sure the stuffing is evenly distributed for the best results.

Step 8: Moisten the Stuffing
Carefully pour 1.5 cups of chicken broth over the stuffing mix, allowing it to soak in and moisten. This step is crucial as it ensures the stuffing cooks properly and becomes fluffy, contributing to the overall texture of your Chicken and Stuffing Casserole.

Step 9: Bake the Casserole
Cover the baking dish tightly with foil and bake it in the preheated oven for 40 to 45 minutes. This initial covered baking allows the chicken to cook through and the flavors to meld together beautifully.

Step 10: Brown the Top
Remove the foil after the initial baking time and return the casserole to the oven for an additional 5 minutes. This will help brown the top, giving it a delightful crispy texture while completing your Chicken and Stuffing Casserole.

Step 11: Check for Doneness
Before serving, ensure the chicken has reached an internal temperature of 165°F (74°C). This is crucial for safety and ensures that the chicken is juicy and tender. Optionally, garnish with fresh or dried parsley for a pop of color before serving.

Step 12: Serve and Enjoy
Once your Chicken and Stuffing Casserole is golden and bubbling, remove it from the oven. Allow it to cool for a few minutes, then scoop out portions and serve warm. This comforting dish is sure to bring smiles around the dinner table!

Expert Tips for Chicken and Stuffing Casserole

Chicken Size Matters: Cut chicken tenderloins into uniform pieces to ensure even cooking throughout your Chicken and Stuffing Casserole.
Sauce Consistency: Whisk sauces thoroughly to avoid lumps; a smooth blend ensures an even coating on the chicken for better flavor.
Avoid Soggy Stuffing: Pour the chicken broth gently over the stuffing to moisten it without making it overly wet; this maintains texture.
Cover Properly: Ensure the baking dish is tightly covered with foil during the first baking step to keep moisture in, leading to a tender casserole.
Check for Doneness: Always use a meat thermometer to check that the chicken reaches 165°F (74°C) for safety and optimal juiciness before serving.

Chicken and Stuffing Casserole Variations

Feel free to get creative with this comforting casserole and make it your own!

Vegetarian Delight: Use seitan or thick-sliced portobello mushrooms instead of chicken for a delicious meat-free option. The hearty mushrooms add depth and a lovely umami flavor.
Creamy Alternatives: Swap cream of celery soup for cream of mushroom or a homemade white sauce for a personalized touch. This allows for a variety of flavors while keeping things creamy.
Herb Infusion: Add fresh herbs like thyme or rosemary to the sauce for an aromatic twist that brightens the dish. A hint of fresh herbs elevates the entire experience!
Savory Crunch: Mix in some crushed herbs or nuts with the stuffing mix to add an extra layer of crunchy texture. This little change can make every bite more exciting.
Cheesy Goodness: Sprinkle shredded cheddar or mozzarella cheese over the stuffing mix before the final bake. This cheesy layer melts beautifully, adding richness and flavor.
Spice It Up: For a kick, add a dash of cayenne pepper or red pepper flakes to the sauce. A little heat pairs surprisingly well with the richness of the casserole.
Fruit Twist: Toss in some chopped apples or dried cranberries for a hint of sweetness. The contrast of flavors can turn this comforting dish into something special for the family.
Leftover Love: Transform any leftover vegetables by layering them into the casserole. Think green beans or broccoli for a nutritious boost, which would complement dishes like Vegetable Casserole Cozy perfectly!

With these variations, your Chicken and Stuffing Casserole can shine bright in so many delightful ways. Enjoy your culinary adventure!

Storage Tips for Chicken and Stuffing Casserole

Fridge: Store leftover Chicken and Stuffing Casserole in an airtight container in the refrigerator for up to 3 days. This helps maintain freshness and flavor while keeping it easy to reheat.
Freezer: For longer storage, freeze the casserole tightly wrapped in plastic wrap and foil for up to 2 months. This is a great way to keep your comfort food ready for a future meal.
Reheating: When ready to enjoy again, thaw overnight in the fridge if frozen. Reheat in the oven at 350°F until heated through for a crispy topping, or use the microwave for quicker results.
Serving Tip: Always check the internal temperature during reheating to ensure it reaches 165°F before serving, keeping your Chicken and Stuffing Casserole safe and delicious!

What to Serve with Easy Chicken and Stuffing Casserole

A delightful meal deserves an equally satisfying companion to bring everything together, enhancing every bite of comfort food bliss.

Steamed Green Beans: Freshly steamed green beans add a crisp texture that contrasts beautifully with the creamy casserole, offering a refreshing bite.
Garlicky Breadsticks: Soft, warm breadsticks drizzled with garlic butter are perfect for soaking up the delicious creamy sauce, providing a comforting sidekick to your meal.
Mixed Green Salad: A simple mixed green salad with a light vinaigrette brings a fresh, zesty element to balance the richness of the casserole, inviting your taste buds to rejoice.
Cranberry Sauce: Sweet and tangy cranberry sauce can brighten the savory flavors of the casserole, giving an unexpected but delightful burst of taste with each forkful.
Honey-Glazed Carrots: Sweet, honey-glazed carrots provide a warm, inviting flavor that complements the casserole’s comforting qualities while adding a bit of color to your plate.
Creamy Mashed Potatoes: Rich and fluffy mashed potatoes create an indulgent pairing, perfect for those who crave a heartier meal. Together, they evoke nostalgic family dinners.
Apple Pie: For dessert, a slice of warm apple pie with a scoop of vanilla ice cream offers a sweet ending that resonates with cozy home-cooked meals, leaving everyone satisfied.

Pair these sides with the cherished Easy Chicken and Stuffing Casserole, and you’ll create a meal that wraps warmth and flavor around every dish, making any night feel special!

Make Ahead Options

These Easy Chicken and Stuffing Casseroles are perfect for meal prep enthusiasts! You can assemble the entire casserole up to 24 hours in advance and refrigerate it until you’re ready to bake. Begin by following the recipe instructions up to the baking point—simply cover the dish tightly with foil or plastic wrap to prevent drying out. When you’re ready to serve, simply remove the cover and bake in a preheated oven at 375°F for about 45 to 50 minutes, adding an extra 5 minutes uncovered to achieve that crispy topping. Trust me, this make-ahead method ensures your casserole is just as delicious while saving you precious time on busy weeknights!

Easy Chicken and Stuffing Casserole Recipe FAQs

How can I ensure the chicken is tender in the casserole?
Absolutely! To keep the chicken tender, make sure to cut the tenderloins into bite-sized pieces so they cook evenly. Additionally, ensure that every piece is well-coated with the creamy sauce, which helps lock in moisture as it bakes.

What’s the best way to store leftovers?
After enjoying your meal, cover any leftover Chicken and Stuffing Casserole tightly in an airtight container and store it in the refrigerator for up to 3 days. This keeps the flavors fresh while making it easy for you to reheat later.

Can I freeze the casserole for later use?
Yes! To freeze your Chicken and Stuffing Casserole, wrap it tightly in both plastic wrap and aluminum foil, ensuring there are no air pockets. It will keep well in the freezer for up to 2 months. When you’re ready, thaw it in the fridge overnight before reheating.

What’s the best way to reheat the casserole?
For best results, reheat your casserole in the oven. Preheat to 350°F (175°C), cover with foil to maintain moisture, and bake until heated through, about 20-30 minutes. Alternatively, you can microwave it for quicker results, but be sure to check that it reaches an internal temperature of 165°F (74°C) before serving!

Are there any dietary substitutions I can make?
Very! If you’re looking for a lighter version, consider using lower-fat cream soups, or replace the chicken with a plant-based protein such as seitan or large portobello mushrooms. You can also switch out the stuffing mix for homemade bread cubes mixed with herbs and spices to suit your dietary needs.

How do I know if the casserole is fully cooked?
To ensure your Chicken and Stuffing Casserole is cooked properly, use a meat thermometer to check that the chicken in the center has reached an internal temperature of 165°F (74°C). This guarantees that it’s safe to eat while also ensuring juicy chicken texture.