Jump to Recipe Print RecipeHave you ever found yourself in a culinary bind, wondering how to elevate your dinner plans? Picture this: a cozy night in, where you’re not just cooking, but crafting an unforgettable meal—welcome to the world of Garlic Butter Shrimp Scampi Lasagna! This unique dish unites the rich flavors of succulent shrimp bathed in creamy garlic butter sauce, layered between tender lasagna noodles. Not only is it a showstopper for gatherings, but its versatility allows you to swap in chicken or veggies, making it a perfect fit for any occasion. Plus, it can be made ahead of time and even frozen for later, freeing you from last-minute stress. Intrigued by how this luxurious comfort food could transform your dining experience? Let’s dive into the recipe! Why Choose Garlic Butter Shrimp Scampi Lasagna? Unforgettable Flavor: Each bite of this lasagna is an explosion of rich garlic and butter combined with fresh shrimp, creating a dish that feels both comforting and gourmet. Customizable Options: Whether you’re a seafood lover or craving a veggie-packed meal, this recipe allows for easy substitutions—try it with chicken or sautéed vegetables for a unique twist. Make-Ahead Convenience: This dish can be prepared in advance, making it perfect for busy weekdays or special occasions. Plus, leftovers freeze beautifully, so you’ll never waste a meal! Quick and Easy Assembly: With simple, accessible ingredients, even novice cooks can master this recipe in no time—just layer, bake, and enjoy! Impressiveness on Display: Ideal for entertaining guests, this stunning lasagna is a sure way to wow friends and family with your cooking skills. Pair it with a crisp side salad or some crusty garlic bread for a complete experience! For more delicious options, don’t miss out on our Garlic Butter Chicken or Coconut Shrimp Thai recipes! Garlic Butter Shrimp Scampi Lasagna Ingredients For the Lasagna Layers • Lasagna Noodles – Use no-boil noodles for ease and time-saving. • Shrimp – Opt for large, fresh shrimp for the best flavor and texture; chicken or veggies are great substitutes. • Mozzarella Cheese – Choose whole milk mozzarella for that perfect melt; vegan cheese works well for a dairy-free alternative. For the Garlic Butter Sauce • Butter – Adds a rich, creamy depth to the sauce; try olive oil for a lighter option. • Minced Garlic – Fresh garlic offers robust flavor; dried garlic powder can be a quick substitute. • Flour – Serves as a thickening agent in the sauce; cornstarch is a great gluten-free option. • Milk – Provides creaminess; low-fat milk can be used for a lighter sauce. • Parmesan Cheese – Adds a nutty richness; nutritional yeast is a wonderful dairy-free alternative. For Seasoning and Garnish • Salt and Pepper – Essential for balancing flavors; adjust to your taste. • Chopped Parsley – Fresh parsley enhances presentation and adds a pop of flavor; feel free to skip if you prefer a simplified dish. Enjoy the seamless fusion of flavors in this Garlic Butter Shrimp Scampi Lasagna, making it a delightful centerpiece for your next meal! Step‑by‑Step Instructions for Garlic Butter Shrimp Scampi Lasagna Step 1: Prepare the Noodles Begin by boiling a large pot of salted water and cooking the lasagna noodles according to package instructions until al dente, about 8-10 minutes. Once finished, carefully drain the noodles in a colander and rinse them under cold water to prevent sticking. Lay the noodles flat on a clean kitchen towel or parchment paper while you prepare the garlic butter shrimp scampi sauce. Step 2: Sauté the Garlic In a large skillet over medium heat, melt 4 tablespoons of butter until it bubbles gently. Add 4 cloves of minced garlic to the skillet and sauté for 1-2 minutes, or until fragrant and lightly golden, stirring frequently to prevent burning. This aromatic base will give your Garlic Butter Shrimp Scampi Lasagna its irresistible flavor. Step 3: Cook the Shrimp Add 1 pound of large shrimp to the skillet, ensuring they’re in a single layer. Sauté for 2-3 minutes per side, or until the shrimp turn pink and opaque. Once cooked, remove the shrimp from the skillet and set aside on a plate, allowing the residual garlic butter to develop even more flavor for the sauce. Step 4: Make the Sauce In the same skillet, add another tablespoon of butter and sprinkle in 2 tablespoons of flour, whisking continuously for about 1 minute until the mixture is bubbly and lightly golden. Gradually incorporate 2 cups of milk, whisking until smooth. Cook for 3-5 minutes until the sauce thickens enough to coat the back of a spoon, ensuring a creamy texture for your Garlic Butter Shrimp Scampi Lasagna. Step 5: Add Cheese and Season Once the sauce has thickened, stir in 1 cup of grated Parmesan cheese until it melts and combines beautifully. Season your sauce with salt and freshly cracked pepper to taste, stirring well to blend all the flavors together. Your garlic butter sauce is now rich and velvety, ready to embrace the layers of lasagna! Step 6: Preheat the Oven Preheat your oven to 375°F (190°C) to ensure it’s hot and ready for baking. This step is crucial for achieving that perfect golden crust on the top of your Garlic Butter Shrimp Scampi Lasagna. While the oven is heating, get your baking dish ready for assembling those delicious layers. Step 7: Layer the Lasagna In a 9×13 inch baking dish, spread a thin layer of the garlic butter sauce on the bottom. Lay down 3-4 lasagna noodles side by side, followed by another layer of sauce, a handful of sautéed shrimp, and a sprinkle of mozzarella cheese. Repeat these layers until all ingredients are used, finishing with a generous layer of sauce topped with mozzarella for that delightful cheesy finish. Step 8: Bake the Lasagna Cover the baking dish tightly with aluminum foil and place it in the preheated oven. Bake for 25 minutes to allow the flavors to meld and the noodles to cook. After this time, remove the foil and continue baking for an additional 10 minutes until the top is bubbling and golden brown, creating a mouthwatering crust on your Garlic Butter Shrimp Scampi Lasagna. Step 9: Garnish and Serve Once baked to perfection, remove the lasagna from the oven and let it cool for about 10 minutes. This resting period makes serving easier and allows the flavors to set beautifully. Garnish your Garlic Butter Shrimp Scampi Lasagna with chopped parsley for a fresh touch before slicing and serving. Enjoy every savory bite! Make Ahead Options These Garlic Butter Shrimp Scampi Lasagna layers are perfect for meal prep enthusiasts! You can assemble the entire lasagna up to 24 hours in advance by constructing it in a baking dish, covering it tightly with plastic wrap, and refrigerating. This not only preserves the flavors but also allows the noodles to soften and soak up that delicious garlic butter sauce overnight. If you prefer, you can prepare the sauce and cook the shrimp separately, storing them in the refrigerator for up to 3 days. When ready to serve, simply preheat your oven and bake the lasagna as directed, adding an extra 5-10 minutes to ensure it’s heated through and bubbly. This way, you’ll have an impressive and comforting dinner on the table with minimal effort! Garlic Butter Shrimp Scampi Lasagna Variations Feel free to sprinkle your creativity into this delightful dish! Let your taste buds lead the way. Chicken Option: Swap out shrimp for cooked chicken, seasoned and shredded, for a comforting twist on this classic. Vegetarian Delight: Replace shrimp with sautéed vegetables like zucchini, bell peppers, and mushrooms, embracing a colorful, hearty alternative. Gluten-Free Choice: Use gluten-free lasagna noodles and cornstarch as a thickener to make this dish friendly for those avoiding gluten. Dairy-Free Treat: Opt for coconut milk and vegan cheese to keep it creamy and rich without any dairy, perfect for lactose-intolerant eaters. Spicy Kick: Add red pepper flakes to the garlic butter sauce to turn up the heat and excite your taste buds with a fiery edge. Herb Infusion: Toss in fresh basil or thyme with the sauce to enhance the aroma and flavor, transporting you straight to Italy! Seafood Medley: Mix in crab or scallops for an extravagant seafood lasagna that takes the flavor profile to the next level. Extra Creaminess: Incorporate a dollop of cream cheese or mascarpone into the sauce for a luxurious, velvety finish that’s hard to resist. For even more delicious inspiration, check out our Cheesy Garlic Chicken Wraps or take a twist with our Spicy Shrimp Avocado recipes! How to Store and Freeze Garlic Butter Shrimp Scampi Lasagna Fridge: Store any leftovers in an airtight container for up to 3 days. Ensure it’s completely cooled before sealing to prevent condensation. Freezer: This lasagna freezes well! Assemble it fully (but don’t bake) and wrap tightly for up to 3 months. Thaw overnight in the fridge before baking. Reheating: Reheat leftovers in a preheated oven at 350°F (175°C) for about 20-30 minutes, covered with foil, until heated through. Enjoy the creamy goodness of your Garlic Butter Shrimp Scampi Lasagna! Make-Ahead: You can prepare and refrigerate the assembled dish up to 24 hours in advance; just add 10 extra minutes to your baking time. Expert Tips for Garlic Butter Shrimp Scampi Lasagna Layer Smartly: Ensure even distribution of shrimp, sauce, and cheese in each layer. This guarantees every bite of your Garlic Butter Shrimp Scampi Lasagna is packed with flavor. Perfectly Cooked Noodles: Avoid overcooking the lasagna noodles; they should be just al dente. They will continue cooking as they bake in the sauce. Versatile Ingredients: Don’t hesitate to swap out shrimp for chicken or seasonal veggies. This keeps the dish exciting and suits various dietary preferences! Sauce Balance: Taste your garlic butter sauce before layering—a sprinkle more salt or pepper can elevate the overall taste of the dish beautifully. Baking Time Adjustments: If you’ve chilled the assembled lasagna overnight, increase baking time to ensure it’s heated thoroughly and bubbly throughout. What to Serve with Garlic Butter Shrimp Scampi Lasagna? A delightful meal is just around the corner, full of flavor and warmth that you’ll want to savor. Crispy Garlic Bread: Perfectly toasted and infused with garlic, it complements the creamy richness of the lasagna while providing a crunchy contrast. Simple Green Salad: Fresh greens with a light vinaigrette add brightness and balance, cutting through the richness of the dish wonderfully. Roasted Vegetables: A medley of seasonal vegetables enhances the meal with their caramelized sweetness, adding a nice texture and color. Refreshing Lemonade: This zesty drink invigorates the palate and pairs beautifully with the savory flavors of the lasagna. Sautéed Spinach: Lightly seasoned spinach adds a pop of freshness and earthy flavors, balancing the decadence of the shrimp scampi. Chilled White Wine: A glass of crisp Sauvignon Blanc or Pinot Grigio elevates the dining experience, enhancing the seafood flavors. Dessert Option: For a sweet finish, consider serving light lemon sorbet, which cleanses the palate after a luxurious meal. Creamy Risotto: Serve a small portion as a side; its creamy texture echoes the lasagna, creating a comforting harmony on your plate. Caprese Skewers: Fresh mozzarella, basil, and cherry tomatoes create a light, vibrant appetizer that whets the appetite wonderfully. Garlic Butter Shrimp Scampi Lasagna Recipe FAQs How do I choose the best shrimp for my lasagna? Absolutely! When selecting shrimp, look for large, fresh shrimp that are firm and intact. Avoid shrimp with dark spots or a strong fishy smell. If you can, opt for wild-caught shrimp for better flavor. If you’re not a fan of seafood, substituting with cooked chicken or sautéed vegetables will still give you a delightful dish. How long can I store leftover Garlic Butter Shrimp Scampi Lasagna? Very! You can store leftovers in an airtight container in the fridge for up to 3 days. Make sure to let it cool completely before sealing to prevent condensation and keep the lasagna fresh. Just reheat in the oven for that freshly baked taste! Can I freeze my Garlic Butter Shrimp Scampi Lasagna? Of course! To freeze, assemble the lasagna but do not bake it. Wrap it tightly in plastic wrap and then foil to prevent freezer burn, and it will last up to 3 months. When you’re ready to enjoy it, simply thaw it in the refrigerator overnight, then bake as directed for a quick, hearty meal! What should I do if my sauce is too thick? If you find your garlic butter sauce is too thick, no worries! Gradually whisk in a little more milk over low heat until you reach your desired consistency. If it’s too thin, just continue to simmer it over low heat until it thickens up a bit. Always taste and adjust your seasonings! Are there any dietary considerations I should be aware of? Absolutely! This recipe can be made gluten-free by using gluten-free lasagna noodles and cornstarch as a thickener. For dairy-free options, substitute milk with almond or coconut milk, and use nutritional yeast instead of Parmesan cheese. If you have seafood allergies, feel free to swap shrimp with chicken or hearty veggies. Your loved ones will appreciate the consideration! How can I tell when my Garlic Butter Shrimp Scampi Lasagna is done baking? The best way to know if your lasagna is done is to look for a bubbling and golden top with melted cheese. If you gently shake the dish, the center should be set and not wobbly. Let it rest for about 10 minutes before serving, as it will continue to cook slightly during that time and will be easier to slice! Garlic Butter Shrimp Scampi Lasagna: Comfort in Every Bite Discover the irresistible Garlic Butter Shrimp Scampi Lasagna, a dish that pairs succulent shrimp with creamy garlic sauce and layers of tender noodles. Print Recipe Pin Recipe Prep Time 30 minutes minsCook Time 40 minutes minsCooling Time 10 minutes minsTotal Time 1 hour hr 20 minutes mins Servings: 6 slicesCourse: DinnerCuisine: ItalianCalories: 600 Ingredients Equipment Method Nutrition Notes Ingredients 1x2x3x? For the Lasagna Layers12 noodles Lasagna Noodles Use no-boil noodles for ease and time-saving.1 pound Shrimp Opt for large, fresh shrimp; chicken or veggies are great substitutes.2 cups Mozzarella Cheese Choose whole milk mozzarella for that perfect melt; vegan cheese works well for a dairy-free alternative.For the Garlic Butter Sauce4 tablespoons Butter Adds a rich, creamy depth to the sauce; try olive oil for a lighter option.4 cloves Minced Garlic Fresh garlic offers robust flavor; dried garlic powder can be a quick substitute.2 tablespoons Flour Serves as a thickening agent; cornstarch is a gluten-free option.2 cups Milk Provides creaminess; low-fat milk can be used for a lighter sauce.1 cup Parmesan Cheese Adds a nutty richness; nutritional yeast is a wonderful dairy-free alternative.For Seasoning and Garnishto taste Salt Essential for balancing flavors.to taste Pepper Essential for balancing flavors.1/4 cup Chopped Parsley Fresh parsley enhances presentation and adds a pop of flavor. Equipment Large PotcolanderLarge SkilletWhisk9x13 inch baking dish Method Step-by-Step Instructions for Garlic Butter Shrimp Scampi LasagnaPrepare the Noodles: Begin by boiling a large pot of salted water and cooking the lasagna noodles according to package instructions until al dente, about 8-10 minutes. Once finished, carefully drain the noodles in a colander and rinse them under cold water to prevent sticking. Lay the noodles flat on a clean kitchen towel or parchment paper while you prepare the garlic butter shrimp scampi sauce.Sauté the Garlic: In a large skillet over medium heat, melt 4 tablespoons of butter until it bubbles gently. Add 4 cloves of minced garlic to the skillet and sauté for 1-2 minutes, or until fragrant and lightly golden, stirring frequently to prevent burning.Cook the Shrimp: Add 1 pound of large shrimp to the skillet, ensuring they're in a single layer. Sauté for 2-3 minutes per side, or until the shrimp turn pink and opaque. Once cooked, remove the shrimp from the skillet and set aside on a plate.Make the Sauce: In the same skillet, add another tablespoon of butter and sprinkle in 2 tablespoons of flour, whisking continuously for about 1 minute until the mixture is bubbly and lightly golden. Gradually incorporate 2 cups of milk, whisking until smooth. Cook for 3-5 minutes until the sauce thickens enough to coat the back of a spoon.Add Cheese and Season: Once the sauce has thickened, stir in 1 cup of grated Parmesan cheese until it melts and combines beautifully. Season your sauce with salt and freshly cracked pepper to taste, stirring well.Preheat the Oven: Preheat your oven to 375°F (190°C).Layer the Lasagna: In a 9x13 inch baking dish, spread a thin layer of the garlic butter sauce on the bottom. Lay down 3-4 lasagna noodles side by side, followed by another layer of sauce, a handful of sautéed shrimp, and a sprinkle of mozzarella cheese. Repeat these layers until all ingredients are used.Bake the Lasagna: Cover the baking dish tightly with aluminum foil and place it in the preheated oven. Bake for 25 minutes. After this time, remove the foil and continue baking for an additional 10 minutes until the top is bubbling and golden brown.Garnish and Serve: Once baked, remove the lasagna from the oven and let it cool for about 10 minutes. Garnish your Garlic Butter Shrimp Scampi Lasagna with chopped parsley before slicing and serving. Nutrition Serving: 1sliceCalories: 600kcalCarbohydrates: 50gProtein: 30gFat: 30gSaturated Fat: 15gPolyunsaturated Fat: 5gMonounsaturated Fat: 5gCholesterol: 150mgSodium: 800mgPotassium: 600mgFiber: 3gSugar: 5gVitamin A: 500IUVitamin C: 2mgCalcium: 300mgIron: 2mg NotesEnsure even distribution of shrimp, sauce, and cheese in each layer. You can also swap out shrimp for chicken or seasonal veggies. Tried this recipe?Let us know how it was!
